Revolutionizing Cryogenic Chemistry with Continuous Flow Technology
The CryoFlowSkid is designed for safe, efficient, and scalable production of cryogenic reactions, such as organometallic syntheses using organolithiums or Grignard reagents. By transitioning from batch to continuous flow, this system enables faster reactions, enhanced heat transfer, and improved process control.
The modular, plug-and-play design allows for multi-step synthesis in a single system, offering superior scalability and process reproducibility. Designed with cutting-edge 3D-printed reactors, the CryoFlowSkid is optimized for high-performance reaction kinetics and temperature control, ensuring precision and efficiency even at ultra-low temperatures.
Performance & Safety
Continuous kg-scale production – High-yield cryogenic reactions with precision control
Safe handling of organometallics – Enhanced containment for reactive compounds
Multi-step synthesis in a single system (-60°C to 100°C / -76°F to 212°F)
Fully automated operation – Intuitive control system for reproducibility and efficiency
Unlocking the future of cryogenic synthesis
Cryogenic reactions require precise thermal management and fast heat dissipation to maintain reaction efficiency and selectivity. The CryoFlowSkid utilizes highly conductive materials and advanced reactor designs, ensuring superior heat transfer and rapid processing compared to traditional batch systems. The system’s integrated automation and safety features make it an ideal choice for pilot plants and industrial-scale production.
Key Applications
Production of APIs and pharmaceutical intermediates with ultra-low temperature reactions
Organolithium and Grignard reagent synthesis for fine chemical manufacturing
Cryogenic reaction development for specialty chemicals
Multi-step continuous synthesis in pilot and production-scale operations
Scalable, Plug-and-Play Cryogenic Process Solutions
The CryoFlowSkid is designed for seamless integration into existing production facilities, with a mobile, explosion-proof design for zone 2 compliance. With quick-connect utility interfaces and modular scalability, the system adapts to various reaction scales and chemistries, ensuring optimal efficiency and minimal downtime.